Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 5/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 2/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.56 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574724 | 0.93 | CYP3A4 (0.74) | ADH5CYP3A4BAZ2BMEN1ALOX15 | |
| SCHEMBL16703118 | 0.86 | CYP3A4 (0.69) | ADH5CYP3A4BAZ2BMEN1ALOX15 | |
| SCHEMBL10480648 | 0.86 | HTT (0.68) | ADH5CYP3A4BAZ2BMEN1ALOX15 | |
| SCHEMBL5307055 | 0.85 | MAOB (0.67) | ADH5CYP3A4BAZ2BMAPTHTT | |
| SCHEMBL6324509 | 0.85 | MAPT (0.74) | ADH5CYP3A4BAZ2BMAPTHTT | |
| SCHEMBL62049 | 0.84 | ADH5 (0.90) | ADH5CYP3A4BAZ2BMEN1ALOX15 | |
| SCHEMBL21940149 | 0.84 | CYP3A4 (0.62) | ADH5CYP3A4BAZ2BMAPTHTT | |
| SCHEMBL611406 | 0.83 | CYP3A4 (0.65) | ADH5CYP3A4BAZ2BMEN1ALOX15 | |
| Hydrochloric Acid SCHEMBL6152702 | 0.83 | ADH5 (0.87) | ADH5CYP3A4BAZ2BMEN1ALOX15 | |
| SCHEMBL27893085 | 0.83 | ADH5 (0.87) | ADH5CYP3A4BAZ2BMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10189987-B2 | Pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2019-01-29 | — | — | US | disclosed |
| EP-3064546-B1 | PNEUMATIC TIRE | SUMITOMO RUBBER IND (JP) | 2018-08-29 | — | — | EP | disclosed |
| US-9932460-B2 | Rubber composition and pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2018-04-03 | — | — | US | disclosed |
| EP-2857446-B1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER IND (JP) | 2018-03-07 | — | — | EP | disclosed |
| US-9790359-B2 | Tread rubber composition and pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2017-10-17 | — | — | US | disclosed |
| EP-2061450-B1 | METHODS OF MODULATING CELL PROLIFERATION AND CYST FORMATION IN POLYCYSTIC KIDNEY AND LIVER DISEASES | MEDICAL COLLEGE WISCONSIN INC (US) | 2017-04-19 | — | — | EP | disclosed |
| US-9511072-B2 | Methods of modulating cell proliferation and cyst formation in polycystic kidney and liver diseases | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-9511072-B2 | Methods of modulating cell proliferation and cyst formation in polycystic kidney and liver diseases | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20160264772-A1 | PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2016-09-15 | — | — | US | disclosed |
| EP-2674457-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER IND (JP) | 2016-09-14 | — | — | EP | disclosed |
| US-20080167382-A1 | By administering a 20-hydroxyeicosatetraenoic acid (20-HETE) synthesizing enzyme inhibitor or a 20-HETE antagonist; antiproliferative agents | THE MEDICAL COLLEGE OF WISCONSIN, INC. | 2008-07-10 | — | — | US | disclosed |
| WO-2008034011-A2 | METHODS OF MODULATING CELL PROLIFERATION AND CYST FORMATION IN POLYCYSTIC KIDNEY AND LIVER DISEASES | MCW RESEARCH FOUNDATION, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| US-7339005-B2 | Process for producing modified diene polymer rubber | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-03-04 | — | — | US | disclosed |
| CN-1330678-C | Method for preparing modified dienopolymer rubber | SUMITOMO CHEMICAL CO (JP) | 2007-08-08 | — | — | CN | disclosed |
| CN-1326896-C | Process for producing modified polymer rubber | SUMITOMO CHEMICAL CO (JP) | 2007-07-18 | — | — | CN | disclosed |
| US-6806321-B2 | PRODUCING MATERIAL FOR FUEL CONSERVATIVE MOTORCAR TIRES; CATALYTIC POLYMERIZATION OF CONJUGATED DIENE AND AROMATIC VINYL MONOMERS THEN REACTING WITH KETONE DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-10-19 | — | — | US | disclosed |
| CN-1530379-A | Method for preparing modified dienopolymer rubber | 住友化学工业株式会社 | 2004-09-22 | — | — | CN | disclosed |
| US-20040152845-A1 | Process for producing modified diene polymer rubber | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-05 | — | — | US | disclosed |
| US-20040054092-A1 | Process for producing modified polymer rubber | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-03-18 | — | — | US | disclosed |
| CN-1482150-A | Process for producing modified polymer rubber | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-03-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167382-A1 | By administering a 20-hydroxyeicosatetraenoic acid (20-HETE) synthesizing enzyme inhibitor or a 20-HETE antagonist; antiproliferative agents | PKD1, PKD2, ALOX15 | ADH5 2699/4885CYP3A4 2013/4885BAZ2B 2660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.