Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088975 | 0.90 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2GPBAR1PTGDR2NR4A2 | |
| SCHEMBL6089372 | 0.89 | CYSLTR1 (0.62) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6090791 | 0.86 | PTGDR2 (0.44) | PTGDR2NR4A1NR4A2NR4A3 | |
| SCHEMBL6091468 | 0.86 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2GPBAR1PTGDR2 | |
| SCHEMBL6090629 | 0.86 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2GPBAR1NR4A1NR4A2 | |
| SCHEMBL6092367 | 0.84 | LMNA (0.48) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6087773 | 0.84 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1PTGDR2 | |
| SCHEMBL6088840 | 0.84 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6088575 | 0.83 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6089788 | 0.83 | CYSLTR1 (0.43) | CYSLTR1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |
| EP-1177176-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064876-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |