Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089086 | 0.86 | CYSLTR1 (0.51) | PTGDR2NR4A2NR4A1NR4A3 | |
| SCHEMBL6088420 | 0.83 | NR4A2 (0.38) | NR4A2NR4A1NR4A3NPC1RAB9A | |
| SCHEMBL6088975 | 0.81 | CYSLTR1 (0.46) | PTGDR2NR4A2NPC1RAB9A | |
| SCHEMBL6090648 | 0.80 | MEN1 (0.48) | PTGDR2NR4A2NPC1RAB9ALMNA | |
| SCHEMBL6089372 | 0.79 | CYSLTR1 (0.62) | — | |
| SCHEMBL6090684 | 0.79 | NR4A2 (0.46) | PTGDR2NR4A2NR4A1NR4A3NPC1 | |
| SCHEMBL6089340 | 0.79 | PTGDR2 (0.48) | PTGDR2NR4A2PPARGNPC1RAB9A | |
| SCHEMBL6091468 | 0.77 | CYSLTR1 (0.51) | PTGDR2 | |
| SCHEMBL6092205 | 0.77 | PTGDR2 (0.53) | PTGDR2NR4A2PPARDPPARGNPC1 | |
| SCHEMBL6089768 | 0.77 | MRGPRX4 (0.49) | PTGDR2PPARDPPARGMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |