Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4843386 | 0.80 | SCN4A (0.39) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6090926 | 0.80 | ALDH1A1 (0.51) | NAMPTALDH1A1CA2SMN1; SMN2KDM4E | |
| SCHEMBL22096830 | 0.78 | NAMPT (0.53) | NAMPTALDH1A1CA2SMN1; SMN2KDM4E | |
| SCHEMBL9695178 | 0.77 | NR1H4 (0.38) | ALDH1A1CA2SMN1; SMN2KDM4E | |
| SCHEMBL6771911 | 0.73 | CA2 (0.34) | ALDH1A1CA2SMN1; SMN2KDM4E | |
| SCHEMBL7464494 | 0.71 | PTGER4 (0.33) | SMN1; SMN2 | |
| SCHEMBL10154387 | 0.70 | CYP1A2 (0.47) | NAMPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3175743 | 0.68 | ALDH1A1 (0.44) | ALDH1A1CA2 | |
| SCHEMBL27499107 | 0.68 | PTGER4 (0.36) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9994746 | 0.66 | CA2 (0.61) | ALDH1A1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |
| EP-1177176-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064876-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |