SCHEMBL608919

SCHEMBL608919

COc1ccc(N2CCCCCC2=O)cc1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
F10 P00742 9/20 0.58
F2 P00734 3/20 0.58
SLC29A1 Q99808 1/20 0.56
POLB P06746 1/20 0.54
TP53 P04637 2/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
HTT P42858 1/20 0.52
HIF1A Q16665 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
MAPT P10636 2/20 0.52
ALDH1A1 P00352 3/20 0.51
AKR1C3 P42330 1/20 0.51
HPGD P15428 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL611715 0.98 F10 (0.57) F10F2SLC29A1POLBTP53
SCHEMBL29930365 0.93 TP53 (0.59) F10F2SLC29A1POLBTP53
SCHEMBL609306 0.93 TP53 (0.59) F10F2SLC29A1POLBTP53
SCHEMBL2046118 0.86 POLB (0.61) F10F2SLC29A1POLBTP53
SCHEMBL24262954 0.85 F10 (0.48) F10F2SLC29A1TP53KMT2A
SCHEMBL28020833 0.81 F10 (0.44) F10F2SLC29A1POLBTP53
SCHEMBL4461794 0.81 AKR1C3 (0.55) TP53MEN1KMT2AHTTALDH1A1
SCHEMBL21504279 0.81 NPC1 (0.56) F10POLBTP53MEN1KMT2A
SCHEMBL14217341 0.80 GAA (0.67) TP53KMT2AHTTHIF1ANPSR1
SCHEMBL546307 0.80 HTT (0.47) F10F2SLC29A1TP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10189987-B2 Pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-01-29 US disclosed
EP-3064546-B1 PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-08-29 EP disclosed
CN-105722909-B Pneumatic tire 住友橡胶工业株式会社 2018-04-06 CN disclosed
EP-2857446-B1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-03-07 EP disclosed
US-9790359-B2 Tread rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-10-17 US disclosed
US-20160264772-A1 PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-09-15 US disclosed
EP-2674457-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2016-09-14 EP disclosed
EP-3064546-A1 PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2016-09-07 EP disclosed
CN-103443189-B Rubber composition and pneumatic tire 住友橡胶工业株式会社 2016-09-07 CN disclosed
CN-104334629-B Rubber composition for tire tread and pneumatic tire 住友橡胶工业株式会社 2016-08-24 CN disclosed
US-20130090409-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-04-11 US disclosed
CN-103003348-A Rubber composition and pneumatic tire SUMITOMO RUBBER IND 2013-03-27 CN disclosed
US-8334339-B2 Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL CO., LTD. (JP) 2012-12-18 US disclosed
US-8299167-B2 Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-30 US disclosed
US-20120149806-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. 2012-06-14 US disclosed
EP-2463310-A1 Rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2012-06-13 EP disclosed
US-20120041134-A1 CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER COMPOSITION, AND PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-16 US disclosed
US-20110237737-A1 CONJUGATED DIENE POLYMER RUBBER, AND CONJUGATED DIENE POLYMER RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-29 US disclosed
US-20100056712-A1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-04 US disclosed
US-20090005515-A1 METHOD FOR PRODUCING CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER, AND CONJUGATED DIENE POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-01 US disclosed