Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL611715 | 0.82 | F10 (0.57) | F10F2SLC29A1POLBMEN1 | |
| SCHEMBL608919 | 0.81 | F10 (0.58) | F10F2SLC29A1POLBMEN1 | |
| SCHEMBL27729038 | 0.79 | F10 (0.39) | F10F2SLC29A1MEN1KMT2A | |
| SCHEMBL29930365 | 0.78 | TP53 (0.59) | F10F2SLC29A1POLBMEN1 | |
| SCHEMBL609306 | 0.78 | TP53 (0.59) | F10F2SLC29A1POLBMEN1 | |
| SCHEMBL28751156 | 0.75 | DRD2 (0.38) | F10MEN1KMT2AMAPTHTT | |
| SCHEMBL28020459 | 0.74 | F10 (0.38) | F10F2SLC29A1MEN1KMT2A | |
| SCHEMBL18605054 | 0.74 | ALDH1A1 (0.46) | TP53MAPTHTTHIF1ANPSR1 | |
| SCHEMBL24262954 | 0.73 | F10 (0.48) | F10F2SLC29A1KMT2ATP53 | |
| SCHEMBL27610830 | 0.73 | CHEK1 (0.35) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744461-A | Lactam-containing compounds and derivatives thereof as factor Xa inhibitors | BRISTOL MYERS SQUIBB CO | 2015-07-01 | — | — | CN | disclosed |