Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TPH1 | P17752 | 1/20 | 0.34 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089500 | 0.92 | TPH1 (0.38) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL6086074 | 0.89 | MEN1 (0.35) | HDAC8HDAC6MEN1KMT2ATDP1 | |
| SCHEMBL6086116 | 0.86 | GRIN1 (0.37) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL6087483 | 0.86 | MEN1 (0.43) | MEN1KMT2AMAPK1HPGDTSHR | |
| SCHEMBL6085624 | 0.84 | TYMS (0.36) | TYMSHDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL6086765 | 0.84 | MEN1 (0.38) | MEN1KMT2ATDP1SMN1; SMN2MAPT | |
| SCHEMBL6086524 | 0.84 | HDAC1 (0.39) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL7844325 | 0.83 | TYMS (0.35) | TYMSHDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL12752168 | 0.83 | KMT2A (0.40) | MEN1KMT2ATDP1TPH1TPH2 | |
| SCHEMBL6087754 | 0.81 | KMT2A (0.39) | MEN1KMT2ATDP1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |