Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091834 | 0.81 | PARP1 (0.36) | PARP1TNKS2 | |
| SCHEMBL6087946 | 0.75 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1 | |
| SCHEMBL6087942 | 0.75 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1 | |
| SCHEMBL6091683 | 0.74 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL6091687 | 0.74 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL6091754 | 0.73 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL6091918 | 0.73 | POLB (0.33) | ALDH1A1L3MBTL1PDE3A | |
| SCHEMBL6091916 | 0.73 | POLB (0.33) | ALDH1A1L3MBTL1PDE3A | |
| SCHEMBL6088122 | 0.72 | — | — | |
| SCHEMBL6088125 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |