Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 4/20 | 0.55 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687552 | 0.93 | RELA (0.62) | CA1CA2CA12CA14CA7 | |
| SCHEMBL10596044 | 0.91 | RELA (0.66) | CA1CA2CA12CA14CA7 | |
| SCHEMBL7688965 | 0.91 | RELA (0.66) | CA1CA2CA12CA14CA7 | |
| SCHEMBL10924903 | 0.91 | RELA (0.66) | CA1CA2CA12CA14CA7 | |
| SCHEMBL7687766 | 0.91 | RELA (0.66) | CA1CA2CA12CA14CA7 | |
| SCHEMBL5689484 | 0.90 | CA1 (0.61) | CA1CA2CA12CA14CA7 | |
| SCHEMBL5689488 | 0.90 | CA1 (0.52) | CA1CA2CA12CA14CA7 | |
| SCHEMBL4556568 | 0.88 | RELA (0.68) | CA1CA2CA12CA14CA7 | |
| SCHEMBL23072063 | 0.87 | RELA (0.53) | CA1CA2CA12CA14CA7 | |
| SCHEMBL2051122 | 0.87 | RELA (0.49) | CA1CA2CA12CA14CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9107751-B2 | Injectable and moldable bone substitute materials | WARSAW ORTHOPEDIC, INC. (US) | 2015-08-18 | — | — | US | claimed |
| US-9034356-B2 | Porous osteoimplant | WARSAW ORTHOPEDIC, INC. (US) | 2015-05-19 | — | — | US | claimed |
| EP-1976460-A2 | INJECTABLE AND MOLDABLE BONE SUBSTITUTE MATERIALS | Osteotech, Inc., (US) | 2008-10-08 | — | — | EP | claimed |
| EP-1976459-A2 | POROUS OSTEOIMPLANT | Osteotech, Inc., (US) | 2008-10-08 | — | — | EP | claimed |
| US-20080069852-A1 | Composite containing biocompatible polymer and bone particles | WARSAW ORTHOPEDIC, INC. | 2008-03-20 | — | — | US | claimed |
| US-20070191963-A1 | INJECTABLE AND MOLDABLE BONE SUBSTITUTE MATERIALS | WARSAW ORTHOPEDIC, INC. | 2007-08-16 | — | — | US | claimed |
| WO-2007084609-A2 | POROUS OSTEOIMPLANT | OSTEOTECH, INC. (US) | 2007-07-26 | — | — | WO | claimed |
| WO-2007084725-A2 | INJECTABLE AND MOLDABLE BONE SUBSTITUTE MATERIALS | OSTEOTECH, INC. (US) | 2007-07-26 | — | — | WO | claimed |
| EP-3445411-B1 | AN IMPLANTABLE COMPOSITE CONTAINING CARBONATED HYDROXYAPATITE | WARSAW ORTHOPEDIC INC (US) | 2025-02-19 | — | — | EP | disclosed |
| EP-3362107-B1 | POLY(THIOKETAL-URETHANE) SCAFFOLDS AND METHODS OF USE | UNIV VANDERBILT (US) | 2025-01-15 | — | — | EP | disclosed |
| CN-108601958-B | Pro-fragrance compositions | 爱客多有限公司 | 2022-06-17 | — | — | CN | disclosed |
| US-11324597-B2 | Implantable composite containing carbonated hydroxyapatite | WARSAW ORTHOPEDIC, INC. (US) | 2022-05-10 | — | — | US | disclosed |
| WO-2021061823-A1 | CHEMICAL COMPOUNDS | Boragen, Inc. (US) | 2021-04-01 | — | — | WO | disclosed |
| US-20200038187-A1 | IMPLANTABLE COMPOSITE CONTAINING CARBONATED HYDROXYAPATITE | WARSAW ORTHOPEDIC, INC. | 2020-02-06 | — | — | US | disclosed |
| US-4626537-A | Guanidines, pharmaceutical compositions and use | CIBA-GEIGY CORPORATION (US) | 1986-12-02 | — | — | US | disclosed |
| EP-0020303-B1 | GUANIDINES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING SUCH COMPOUNDS AND THEIR APPLICATION | CIBA-GEIGY AG (CH) | 1985-08-28 | — | — | EP | disclosed |
| US-4272566-A | Suspension agent for synthetic resin powders | CHEMISCHE WERKE HULS AG (DE) | 1981-06-09 | — | — | US | disclosed |
| EP-0020303-A1 | Guanidines, process for their preparation, pharmaceutical preparations containing such compounds and their application | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | disclosed |
| US-4237040-A | Suspension agent for synthetic resin powders | CHEMISCHE WERKE HULS AG (DE) | 1980-12-02 | — | — | US | disclosed |
| US-4039467-A | PLASTIC SUBSTRATE | AMERICAN CYANAMID COMPANY (US) | 1977-08-02 | — | — | US | disclosed |