Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837443 | 0.82 | AHR (0.61) | CYP11B1CYP11B2CYP19A1AHRPDE7A | |
| SCHEMBL2675583 | 0.77 | SRD5A1 (0.57) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL2230502 | 0.77 | NPC1 (0.50) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL1764695 | 0.77 | AHR (0.70) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL29410901 | 0.77 | NPC1 (0.50) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL434004 | 0.77 | NPC1 (0.50) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL3593737 | 0.77 | NPC1 (0.50) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL3593739 | 0.77 | NPC1 (0.50) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| Hydrochloric Acid SCHEMBL29961795 | 0.76 | NPC1 (0.48) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| Hydrochloric Acid SCHEMBL30293224 | 0.76 | SRD5A1 (0.55) | NPC1MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676590-A1 | PHOSPHODIESTERASE 3 (PDE3) INHIBITORS | Zoetis Services LLC (US) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024191714-A1 | PHOSPHODIESTERASE 3 (PDE3) INHIBITORS | ZOETIS SERVICES LLC (US) | 2024-09-19 | — | — | WO | disclosed |
| US-20240308973-A1 | PHOSPHODIESTERASE 3 (PDE3) INHIBITORS | ZOETIS SERVICES LLC | 2024-09-19 | — | — | US | disclosed |
| CN-111587239-B | Method for producing lactam compound and lactam compound produced by the method | 基础科学研究院 | 2024-04-02 | — | — | CN | disclosed |
| US-11332443-B2 | Derivatives of halo quinabactin | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-05-17 | — | — | US | disclosed |
| CN-108349899-B | Derivatives of halogenated quinacrycins | 加利福尼亚大学董事会 | 2021-10-22 | — | — | CN | disclosed |
| US-11046661-B2 | Method for producing lactam compound, and lactam compound produced thereby | INSTITUTE FOR BASIC SCIENCE (KR) | 2021-06-29 | — | — | US | disclosed |
| US-11046661-B2 | Method for producing lactam compound, and lactam compound produced thereby | INSTITUTE FOR BASIC SCIENCE (KR) | 2021-06-29 | — | — | US | disclosed |
| US-20200331871-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | INSTITUTE FOR BASIC SCIENCE (KR) | 2020-10-22 | — | — | US | disclosed |
| US-20200331871-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | INSTITUTE FOR BASIC SCIENCE (KR) | 2020-10-22 | — | — | US | disclosed |
| WO-2019135604-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | 기초과학연구원 | 2019-07-11 | — | — | WO | disclosed |
| WO-2019135604-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | 기초과학연구원 | 2019-07-11 | — | — | WO | disclosed |
| US-20180312470-A1 | DERIVATIVES OF HALO QUINABACTIN | SYNGENTA PARTICIPATIONS AG (CH) | 2018-11-01 | — | — | US | disclosed |
| EP-3341361-A1 | DERIVATIVES OF HALO QUINABACTIN | The Regents of The University of California (US) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017034982-A1 | DERIVATIVES OF HALO QUINABACTIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-02 | — | — | WO | disclosed |
| US-20060004028-A1 | Novel PARP inhibitor | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2006-01-05 | — | — | US | disclosed |
| EP-1582520-A1 | NOVEL PARP INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004108678-A1 | (1,2,3,4-TETRAHYDROQUINOLIN-8-YL)-HEPTATRIENOIC ACID DERIVATIVES HAVING SERUM GLUCOSE REDUCING ACTIVITY | ALLERGAN, INC. (US) | 2004-12-16 | — | — | WO | disclosed |
| US-6734193-B1 | REDUCE SERUM GLUCOSE AND SERUM TRIGLYCERIDE LEVELS IN DIABETIC MAMMALS WITHOUT THE UNDESIRABLE PROPERTIES OF REDUCING SERUM THYROXINE LEVELS AND TRANSIENTLY RAISING TRIGLYCERIDE LEVELS | ALLERGAN, INC. | 2004-05-11 | — | — | US | disclosed |
| US-4349554-A | Method of using carbostyril derivatives as plant fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004028-A1 | Novel PARP inhibitor | PARP1, PARP2, PARP11 | NPC1 3249/4885MAPK13 756/4885MAPK12 868/4885 |
| US-20240308973-A1 | PHOSPHODIESTERASE 3 (PDE3) INHIBITORS | PDE3A, PDE3B, PDE5A | NPC1 3471/4885MAPK13 997/4885MAPK12 2189/4885 |
| US-20200331871-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | SQLE, COASY, DHPS | NPC1 3709/4885MAPK13 4250/4885MAPK12 3592/4885 |
| US-20180312470-A1 | DERIVATIVES OF HALO QUINABACTIN | HDHD5, HSF1, NQO2 | NPC1 3742/4885MAPK13 2013/4885MAPK12 1196/4885 |
| US-11046661-B2 | Method for producing lactam compound, and lactam compound produced thereby | SQLE, COASY, DHPS | NPC1 3709/4885MAPK13 4250/4885MAPK12 3592/4885 |
| US-11332443-B2 | Derivatives of halo quinabactin | HDHD5, HSF1, NQO2 | NPC1 3742/4885MAPK13 2013/4885MAPK12 1196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.