Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.67 |
| ▸ | PGR | P06401 | 5/20 | 0.67 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.67 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CCNK | O75909 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8331367 | 0.86 | NR3C1 (0.66) | ARNR3C1PGRNR3C2 | |
| SCHEMBL6091641 | 0.85 | AR (0.51) | ARNR3C1PGRNR3C2BRPF1 | |
| SCHEMBL1348790 | 0.82 | NR3C1 (0.60) | ARNR3C1PGRNR3C2 | |
| SCHEMBL6090200 | 0.81 | NR3C1 (1.00) | ARNR3C1PGRNR3C2 | |
| SCHEMBL8320352 | 0.81 | NR3C1 (1.00) | ARNR3C1PGRNR3C2 | |
| SCHEMBL6089733 | 0.81 | NR3C1 (1.00) | ARNR3C1PGRNR3C2 | |
| SCHEMBL1350849 | 0.80 | NR3C1 (0.58) | ARNR3C1PGRNR3C2 | |
| SCHEMBL1349908 | 0.80 | NR3C1 (0.70) | ARNR3C1PGRNR3C2 | |
| SCHEMBL6090185 | 0.77 | NR3C1 (0.92) | ARNR3C1PGRNR3C2 | |
| SCHEMBL6088671 | 0.75 | AR (0.40) | ARNR3C1PGRNR3C2BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060235222-A1 | Indole-derivative modulators of steroid hormone nuclear receptors | ELI LILLY AND COMPANY (US) | 2006-10-19 | — | — | US | disclosed |
| WO-2004067529-A1 | INDOLE-DERIVATIVE MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235222-A1 | Indole-derivative modulators of steroid hormone nuclear receptors | NR3C2, NR5A1, MC2R | AR 27/4885NR3C1 4/4885PGR 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.