Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092194 | 0.85 | KDM4E (0.37) | KDM4EPOLBALOX15ALDH1A1L3MBTL1 | |
| SCHEMBL6092919 | 0.84 | MDM2 (0.39) | KDM4EPOLBALOX15FFAR1KCNA5 | |
| SCHEMBL6092501 | 0.84 | KDM4E (0.36) | KDM4EPOLBALOX15ALDH1A1KMT2A | |
| SCHEMBL6092633 | 0.82 | DNMT1 (0.39) | KDM4EPOLBALOX15ALDH1A1L3MBTL1 | |
| SCHEMBL6090159 | 0.81 | CACNA1B (0.38) | KDM4EPOLBALOX15PPARGPPARA | |
| SCHEMBL6094362 | 0.81 | FFAR1 (0.44) | KMT2AFFAR1KCNA5KCNH2 | |
| SCHEMBL6094330 | 0.79 | FFAR1 (0.40) | KDM4EPOLBALOX15FFAR1KCNA5 | |
| SCHEMBL4474014 | 0.78 | FFAR4 (0.40) | KDM4EPOLBALOX15ALDH1A1L3MBTL1 | |
| SCHEMBL6092904 | 0.78 | FFAR1 (0.36) | KDM4EPOLBALOX15ALDH1A1L3MBTL1 | |
| SCHEMBL27552569 | 0.75 | IDO1 (0.38) | KDM4EPOLBALDH1A1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148880-A1 | Isoindolone derivatives, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148880-A1 | Isoindolone derivatives, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them | TNNI3, NDUFB3, NDUFB11 | KDM4E 4143/4885POLB 1575/4885ALOX15 409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.