NDUFB3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20
SCHEMBL8491443	0.56	4/20
SCHEMBL8489900	0.52	4/20
SCHEMBL8489907	0.52	4/20
SCHEMBL8489902	0.51	4/20
SCHEMBL8489908	0.51	4/20
SCHEMBL8491154	0.51	4/20
SCHEMBL8491160	0.51	4/20
SCHEMBL8491619	0.50	4/20
SCHEMBL8491624	0.50	4/20
SCHEMBL8491634	0.50	4/20
7-Prenyloxycoumarin (SCHEMBL4898255)	0.79	3/20
SCHEMBL712741	0.57	3/20
Geiparvarin (SCHEMBL2532495)	0.56	3/20
SCHEMBL6267768	0.55	3/20
SCHEMBL1095981	0.55	3/20
SCHEMBL4293165	0.55	3/20
SCHEMBL8490928	0.53	3/20
SCHEMBL8490937	0.53	3/20

Clinical trials — most relevant to NDUFB3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease	PHASE3	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy	PHASE2	ACTIVE_NOT_RECRUITING
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
Nitrites, Skeletal Muscle Mitochondrial Bioenergetics, and Physical Activity in Old Age	PHASE2	COMPLETED
Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome	PHASE1/PHASE2	COMPLETED
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)	PHASE1/PHASE2	NOT_YET_RECRUITING
Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease	PHASE2	RECRUITING
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Nicotinamide Riboside in Ulcerative Colitis	nan	RECRUITING
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction	nan	COMPLETED
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases	nan	RECRUITING
A RETROspective Study of Patients With TK2d	nan	COMPLETED
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
Genetic Diagnosis in Inborn Errors of Metabolism	nan	ENROLLING_BY_INVITATION
Prospective Observational Study of Trimetazidine Influence on Mitochondrial Metabolism in Human Heart Ventricle	nan	COMPLETED
Cardiac Mitochondrial Function in Explanted Human Hearts	nan	UNKNOWN
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a NDUFB3 binder may also engage these)

Protein	Name	Similarity
Q0MQD1	—	1.000	Q0MQD1 →
Q0MQD2	—	1.000	Q0MQD2 →
Q0MQD0	—	1.000	Q0MQD0 →
Q02365	—	0.997	Q02365 →
Q9CQZ6	—	0.995	Q9CQZ6 →
Q9W380	—	0.991	Q9W380 →
Q86L28	—	0.988	Q86L28 →
C4YTL7	—	0.988	C4YTL7 →
P19173	—	0.988	P19173 →
C5E1G5	—	0.987	C5E1G5 →
B9WK46	—	0.987	B9WK46 →
Q6CHT7	—	0.987	Q6CHT7 →
Q6C9E6	—	0.986	Q6C9E6 →
P26310	—	0.986	P26310 →
A3LWK1	—	0.986	A3LWK1 →
Q9FNE0	—	0.986	Q9FNE0 →
G2TRJ9	—	0.986	G2TRJ9 →
A6ZPQ9	—	0.986	A6ZPQ9 →
C7GR49	—	0.986	C7GR49 →
Q54LT5	—	0.985	Q54LT5 →
Q3E7B2	—	0.985	Q3E7B2 →
Q9CQ91	—	0.985	Q9CQ91 →
Q6BY05	—	0.985	Q6BY05 →
Q9C0X5	—	0.985	Q9C0X5 →
Q6BL60	—	0.985	Q6BL60 →
C5E368	—	0.985	C5E368 →
C0HK65	—	0.985	C0HK65 →
NDUFB4	NADH dehydrogenase [ubiquinone] 1 beta subcom	0.984	landscape →
O94377	—	0.984	O94377 →
Q2KP58	—	0.984	Q2KP58 →