NDUFB11 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL15258558	0.76	8/20
R-(+)-Marmin (SCHEMBL27804600)	0.83	7/20
R-(+)-Marmin (SCHEMBL29353819)	0.83	7/20
R-(+)-Marmin (SCHEMBL29625637)	0.83	7/20
SCHEMBL12362713	0.77	7/20
SCHEMBL15080621	0.77	7/20
SCHEMBL12362702	0.73	7/20
SCHEMBL14351066	0.69	7/20
SCHEMBL12226742	0.61	7/20
SCHEMBL31179835	0.59	7/20
SCHEMBL31397586	0.53	7/20
SCHEMBL31000416	0.78	6/20
SCHEMBL31376481	0.71	6/20
SCHEMBL12362734	0.60	6/20
SCHEMBL12362700	0.57	6/20
SCHEMBL13973668	0.47	6/20
SCHEMBL16316892	0.47	6/20
SCHEMBL24700101	0.44	6/20
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20

Clinical trials — most relevant to NDUFB11 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease	PHASE3	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy	PHASE2	ACTIVE_NOT_RECRUITING
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
Parkinson's Disease Treatment With Coenzyme Q10	PHASE2	COMPLETED
Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome	PHASE1/PHASE2	COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED
Diagnostic Odyssey Survey 2	nan	COMPLETED
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis	nan	UNKNOWN
Nicotinamide Riboside in Ulcerative Colitis	nan	RECRUITING
Ccf mtDNA as a Neurodegenerative Biomarker	nan	UNKNOWN
Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED
Genetic Diagnosis in Inborn Errors of Metabolism	nan	ENROLLING_BY_INVITATION
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction	nan	COMPLETED
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases	nan	RECRUITING
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis	nan	COMPLETED
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a NDUFB11 binder may also engage these)

Protein	Name	Similarity
Q0MQJ3	—	1.000	Q0MQJ3 →
Q0MQJ4	—	1.000	Q0MQJ4 →
Q8HXG5	—	1.000	Q8HXG5 →
Q0MQJ5	—	1.000	Q0MQJ5 →
O09111	—	0.996	O09111 →
Q6DQX6	—	0.991	Q6DQX6 →
Q4QQV3	—	0.985	Q4QQV3 →
Q02380	—	0.984	Q02380 →
Q0MQC9	—	0.984	Q0MQC9 →
P0C2B7	—	0.983	P0C2B7 →
Q0MQC8	—	0.983	Q0MQC8 →
Q9D6U8	—	0.983	Q9D6U8 →
Q9CQH3	—	0.982	Q9CQH3 →
Q0MQC7	—	0.982	Q0MQC7 →
P83565	—	0.982	P83565 →
Q0MQD8	—	0.980	Q0MQD8 →
Q0MQJ0	—	0.980	Q0MQJ0 →
Q5RFR4	—	0.979	Q5RFR4 →
NDUFB5	NADH-ubiquinone oxidoreductase SGDH subunit	0.979	landscape →
NDUFB2	NADH dehydrogenase [ubiquinone] 1 beta subcom	0.979	landscape →
Q9NQ50	—	0.979	Q9NQ50 →
Q9CPU2	—	0.979	Q9CPU2 →
Q0MQD6	—	0.979	Q0MQD6 →
Q9D6J5	—	0.978	Q9D6J5 →
Q2NKR7	—	0.978	Q2NKR7 →
Q6RUT7	—	0.977	Q6RUT7 →
Q02372	—	0.977	Q02372 →
Q5TC12	—	0.977	Q5TC12 →
P60182	—	0.977	P60182 →
Q9D0Y8	—	0.976	Q9D0Y8 →