Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090329 | 1.00 | MAP4K1 (0.32) | MAP4K1 | |
| SCHEMBL6089208 | 0.85 | — | — | |
| SCHEMBL6087575 | 0.81 | MAP4K1 (0.34) | MAP4K1 | |
| SCHEMBL6087571 | 0.81 | MAP4K1 (0.34) | MAP4K1 | |
| SCHEMBL6091586 | 0.79 | TLK2 (0.34) | MAP4K1 | |
| SCHEMBL6091588 | 0.79 | TLK2 (0.34) | MAP4K1 | |
| SCHEMBL6092000 | 0.78 | MAP4K1 (0.33) | MAP4K1 | |
| SCHEMBL6091997 | 0.78 | MAP4K1 (0.33) | MAP4K1 | |
| SCHEMBL6088546 | 0.78 | ALDH1A1 (0.34) | — | |
| SCHEMBL6092325 | 0.77 | PDPK1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |