Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091588 | 1.00 | TLK2 (0.34) | TLK2MAP4K1LRRK2 | |
| SCHEMBL6089018 | 0.86 | PDPK1 (0.41) | TLK2MAP4K1LRRK2 | |
| SCHEMBL6089020 | 0.86 | PDPK1 (0.41) | TLK2MAP4K1LRRK2 | |
| SCHEMBL6091662 | 0.85 | TLK2 (0.34) | TLK2LRRK2 | |
| SCHEMBL6091658 | 0.85 | TLK2 (0.34) | TLK2LRRK2 | |
| SCHEMBL6087575 | 0.82 | MAP4K1 (0.34) | MAP4K1 | |
| SCHEMBL6087571 | 0.82 | MAP4K1 (0.34) | MAP4K1 | |
| SCHEMBL6090338 | 0.79 | MAP4K1 (0.32) | MAP4K1 | |
| SCHEMBL6090329 | 0.79 | MAP4K1 (0.32) | MAP4K1 | |
| SCHEMBL6088079 | 0.78 | ALDH1A1 (0.35) | TLK2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |