Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 8/20 | 0.49 |
| ▸ | CA2 | P00918 | 6/20 | 0.49 |
| ▸ | CA9 | Q16790 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2387841 | 1.00 | CA12 (0.49) | CA12CA2CA9KDM4EMAPT | |
| SCHEMBL22925045 | 0.81 | KMT2A (0.44) | CA12CA2CA9KDM4EMAPT | |
| SCHEMBL6090307 | 0.80 | CA12 (0.50) | CA12CA2CA9KDM4EMAPT | |
| SCHEMBL6090311 | 0.80 | CA12 (0.50) | CA12CA2CA9KDM4EMAPT | |
| SCHEMBL13660695 | 0.79 | CA12 (0.49) | CA12CA2CA9KDM4EMAPT | |
| SCHEMBL348171 | 0.79 | CA12 (0.79) | CA12CA2CA9KDM4EMAPT | |
| SCHEMBL7316721 | 0.79 | CA12 (0.49) | CA12CA2CA9KDM4EMAPT | |
| SCHEMBL7316716 | 0.79 | CA12 (0.49) | CA12CA2CA9KDM4EMAPT | |
| SCHEMBL17660178 | 0.79 | CA12 (0.79) | CA12CA2CA9KDM4EMAPT | |
| SCHEMBL348172 | 0.79 | CA12 (0.79) | CA12CA2CA9KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006059210-A2 | FUSED BICYCLIC PYRROLS AS HMG-COA REDUCTASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-06-08 | — | — | WO | disclosed |