Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090480 | 0.81 | CA12 (0.49) | KMT2AATMSMN1; SMN2CA12CA2 | |
| SCHEMBL2387841 | 0.81 | CA12 (0.49) | KMT2AATMSMN1; SMN2CA12CA2 | |
| SCHEMBL19228736 | 0.77 | ALDH1A1 (0.46) | KMT2ASMN1; SMN2CA12CA2KDM4E | |
| SCHEMBL10309895 | 0.77 | ALDH1A1 (0.46) | KMT2ASMN1; SMN2CA12CA2KDM4E | |
| SCHEMBL31146148 | 0.76 | KMT2A (0.40) | KMT2AATMSMN1; SMN2CA12CA2 | |
| SCHEMBL11977409 | 0.76 | MAPT (0.59) | KMT2AATMSMN1; SMN2CA12CA2 | |
| SCHEMBL13133376 | 0.76 | KMT2A (0.40) | KMT2AATMSMN1; SMN2CA12CA2 | |
| SCHEMBL347780 | 0.75 | CA12 (0.70) | KMT2ASMN1; SMN2CA12CA2KDM4E | |
| SCHEMBL18073251 | 0.75 | LMNA (0.54) | KMT2ASMN1; SMN2CA12CA2KDM4E | |
| SCHEMBL15786312 | 0.75 | CA12 (0.70) | KMT2ASMN1; SMN2CA12CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012264-A1 | TRIAZOLE SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2021-01-28 | — | — | WO | disclosed |