Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090551 | 1.00 | ADORA2B (0.43) | ADORA2BL3MBTL1ALDH1A1POLBPKM | |
| SCHEMBL6091158 | 0.81 | KMT2A (0.43) | ALDH1A1POLBPKMMEN1KMT2A | |
| SCHEMBL6091152 | 0.81 | KMT2A (0.43) | ALDH1A1POLBPKMMEN1KMT2A | |
| SCHEMBL6090504 | 0.80 | ALK (0.41) | ALDH1A1POLBMEN1KMT2ATSHR | |
| SCHEMBL6090494 | 0.80 | ALK (0.41) | ALDH1A1POLBMEN1KMT2ATSHR | |
| SCHEMBL6090275 | 0.79 | KDR (0.52) | ALDH1A1KMT2AMAPTSMN1; SMN2HPGD | |
| SCHEMBL6090289 | 0.79 | KDR (0.52) | ALDH1A1KMT2AMAPTSMN1; SMN2HPGD | |
| SCHEMBL6091559 | 0.78 | JMJD6 (0.34) | L3MBTL1ALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL6091564 | 0.78 | JMJD6 (0.34) | L3MBTL1ALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL6089465 | 0.77 | JMJD6 (0.35) | L3MBTL1ALDH1A1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |