Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.32 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 3/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091564 | 1.00 | JMJD6 (0.34) | JMJD6KDM4EALDH1A1PKN1PKN2 | |
| SCHEMBL6090289 | 0.82 | KDR (0.52) | JMJD6ALDH1A1IMPDH2KDRHPGD | |
| SCHEMBL6090275 | 0.82 | KDR (0.52) | JMJD6ALDH1A1IMPDH2KDRHPGD | |
| SCHEMBL6089465 | 0.81 | JMJD6 (0.35) | JMJD6KDM4EALDH1A1IMPDH2KDR | |
| SCHEMBL6089458 | 0.81 | JMJD6 (0.35) | JMJD6KDM4EALDH1A1IMPDH2KDR | |
| SCHEMBL6090504 | 0.80 | ALK (0.41) | KDM4EALDH1A1IMPDH2KDRHPGD | |
| SCHEMBL6090494 | 0.80 | ALK (0.41) | KDM4EALDH1A1IMPDH2KDRHPGD | |
| SCHEMBL6091158 | 0.78 | KMT2A (0.43) | KDM4EALDH1A1TP53HPGDKMT2A | |
| SCHEMBL6090556 | 0.78 | ADORA2B (0.43) | KDM4EALDH1A1TP53HPGDKMT2A | |
| SCHEMBL6090551 | 0.78 | ADORA2B (0.43) | KDM4EALDH1A1TP53HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |