Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088431 | 0.85 | CYSLTR1 (0.56) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL10546039 | 0.79 | CYSLTR1 (0.66) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6087528 | 0.74 | CYSLTR2 (0.64) | MAPTCYSLTR1CYSLTR2 | |
| SCHEMBL6087530 | 0.74 | CYSLTR2 (0.64) | MAPTCYSLTR1CYSLTR2 | |
| SCHEMBL28230139 | 0.74 | CYP3A4 (0.55) | MAPTHTTSMN1; SMN2CYSLTR1GPBAR1 | |
| SCHEMBL27696506 | 0.74 | MAPT (0.59) | MAPTSMN1; SMN2CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL6088023 | 0.74 | MAPT (0.46) | MAPTHTTSMN1; SMN2CYSLTR1GPBAR1 | |
| SCHEMBL6089769 | 0.73 | CYSLTR1 (0.53) | MAPTHTTSMN1; SMN2CYSLTR1GPBAR1 | |
| SCHEMBL6089044 | 0.73 | DHODH (0.38) | MAPTHTTSMN1; SMN2CYSLTR1GPBAR1 | |
| SCHEMBL6089615 | 0.73 | ABCB1 (0.46) | MAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |
| EP-0780340-B1 | Intercalates and exfoliates formed with functional monomeric organic compounds; composite materials containing same and methods of modifying rheology therewith | AMCOL INTERNATIONAL CORP (US) | 2002-03-20 | — | — | EP | disclosed |
| EP-1177176-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| US-6287634-B1 | INTERCALATION A PHYLLOSILICATE; CONTROLLING MOISTURE CONCENTRATION | AMCOL INTERNATIONAL CORPORATION | 2001-09-11 | — | — | US | disclosed |
| US-6242500-B1 | Intercalates and exfoliates formed with long chain (C6+) or aromatic matrix polymer-compatible monomeric, oligomeric or polymeric intercalant compounds, and composite materials containing same | AMCOL INTERNATIONAL CORPORATION | 2001-06-05 | — | — | US | disclosed |
| WO-2000064876-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |
| US-6124365-A | USEFUL AS PLASTICIZERS AND FOR PROVIDING INCREASED VISCOSITY AND ELASTICITY TO THERMOPLASTIC AND THERMOSETTING POLYMERS, E.G., FOR PLASTICIZING POLYVINYL CHLORIDE; FOR FOOD WRAP HAVING IMPROVED GAS IMPERMEABILITY | AMCOL INTERNATIOANL CORPORATION (US) | 2000-09-26 | — | — | US | disclosed |
| US-6057396-A | INTERCALATE HAVING MOLAR RATIO OF MODIFIER TO INTERLAYER CATION OF ONE TO FIVE TO ACHIEVE SORPTION AND COMPLEXING BETWEEN ADJACENT LAYERS OF MATERIAL TO EXPAND SPACING | AMCOL INTERNATIONAL CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |
| US-5952095-A | AN INTERCALATED PHYLLOSILICATE COMPLEX CAN BE COMBINED WITH AN ORGANIC LIQUID INTO A VISCOUS CARRIER MATERIAL, FOR DELIVERY AN ACTIVE MATERIAL, OR AS PLASTICIZERS FOR AN POLYMER TO FORM A STRONG, FILLED POLYMER MATRIX | AMCOL INTERNATIONAL CORPORATION (US) | 1999-09-14 | — | — | US | disclosed |
| EP-0846662-A2 | Intercalates and exfoliates, their process of manufacture and composites containing them | AMCOL INTERNATIONAL CORPORATION (US) | 1998-06-10 | — | — | EP | disclosed |
| EP-0846661-A2 | Intercalates formed by co-intercalation of monomer, oligomer or polymer intercalants and surface modifier intercalants and layered materials and nanocomposites prepared with the intercalates | AMCOL INTERNATIONAL CORPORATION (US) | 1998-06-10 | — | — | EP | disclosed |
| EP-0846660-A2 | Intercalates and exfoliates formed with long chain monomeric organic intercalant compounds having at least ten carbon atoms and composite materials containing same | AMCOL INTERNATIONAL CORPORATION (US) | 1998-06-10 | — | — | EP | disclosed |
| EP-0780340-A1 | Intercalates and exfoliates formed with functional monomeric organic compounds; composite materials containing same and methods of modifying rheology therewith | AMCOL INTERNATIONAL CORPORATION (US) | 1997-06-25 | — | — | EP | disclosed |