Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | ATP4A | P20648 | 1/20 | 0.31 |
| ▸ | ATP4B | P51164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090610 | 1.00 | PLAT (0.32) | PLATKDRATP4AATP4B | |
| SCHEMBL6092129 | 0.82 | KDR (0.34) | KDR | |
| SCHEMBL6092131 | 0.82 | KDR (0.34) | KDR | |
| SCHEMBL6088734 | 0.77 | KDR (0.37) | KDR | |
| SCHEMBL6090016 | 0.77 | KDM4E (0.34) | — | |
| SCHEMBL6090023 | 0.77 | KDM4E (0.34) | — | |
| SCHEMBL6088730 | 0.77 | KDR (0.37) | KDR | |
| SCHEMBL6090284 | 0.77 | CHEK1 (0.47) | KDR | |
| SCHEMBL6090290 | 0.77 | CHEK1 (0.47) | KDR | |
| SCHEMBL6087969 | 0.76 | LRRK2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |