Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090016 | 0.85 | KDM4E (0.34) | — | |
| SCHEMBL6090023 | 0.85 | KDM4E (0.34) | — | |
| SCHEMBL6091525 | 0.82 | LRRK2 (0.36) | LRRK2 | |
| SCHEMBL6091530 | 0.82 | LRRK2 (0.36) | LRRK2 | |
| SCHEMBL6089109 | 0.77 | CHEK1 (0.46) | — | |
| SCHEMBL6089106 | 0.77 | CHEK1 (0.46) | — | |
| SCHEMBL6088730 | 0.76 | KDR (0.37) | — | |
| SCHEMBL6090618 | 0.76 | PLAT (0.32) | — | |
| SCHEMBL6090610 | 0.76 | PLAT (0.32) | — | |
| SCHEMBL6088734 | 0.76 | KDR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |