Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090648 | 0.86 | MEN1 (0.48) | NR4A2NPC1RAB9ACYSLTR1PTGDR2 | |
| SCHEMBL6089372 | 0.85 | CYSLTR1 (0.62) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL6088975 | 0.85 | CYSLTR1 (0.46) | NR4A2NPC1RAB9ACYSLTR1PTGDR2 | |
| SCHEMBL6088650 | 0.85 | NR4A2 (0.41) | NR4A2NPC1RAB9ACYSLTR1GPBAR1 | |
| SCHEMBL6089086 | 0.83 | CYSLTR1 (0.51) | NR4A2CYSLTR1PTGDR2GPBAR1CYSLTR2 | |
| SCHEMBL6089340 | 0.81 | PTGDR2 (0.48) | NR4A2NPC1RAB9APTGDR2KDM4E | |
| SCHEMBL6088575 | 0.80 | CYSLTR1 (0.54) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL6582234 | 0.79 | CYSLTR1 (0.61) | NPC1CYSLTR1GPBAR1ALDH1A1TSHR | |
| SCHEMBL6092205 | 0.79 | PTGDR2 (0.53) | NR4A2NPC1RAB9APTGDR2MAPK1 | |
| SCHEMBL6088899 | 0.79 | GPBAR1 (0.61) | CYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |