Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960465 | 0.83 | ALDH1A1 (0.50) | HPGDPOLBCA1CA2MEN1 | |
| SCHEMBL6230453 | 0.82 | KMT2A (0.50) | POLBCA1CA2KMT2AALDH1A1 | |
| SCHEMBL4185091 | 0.81 | POLB (0.66) | HPGDPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL25046258 | 0.80 | POLB (0.66) | HPGDPOLBCA1CA2MEN1 | |
| SCHEMBL1798924 | 0.78 | POLB (0.64) | HPGDPOLBCA1CA2MEN1 | |
| SCHEMBL30942706 | 0.78 | POLB (0.59) | HPGDPOLBCA1CA2MEN1 | |
| SCHEMBL165561 | 0.78 | ALDH1A1 (0.46) | HPGDPOLBCA1CA2MEN1 | |
| SCHEMBL63833 | 0.77 | HPGD (0.70) | HPGDPOLBCA1CA2MEN1 | |
| SCHEMBL18392321 | 0.75 | POLB (0.60) | HPGDPOLBCA1CA2MEN1 | |
| SCHEMBL11718244 | 0.75 | RAB9A (0.71) | HPGDPOLBCA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006064286-A1 | CATHEPSIN S INHIBITORS | MEDIVIR UK LTD (GB) | 2006-06-22 | — | — | WO | disclosed |