Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091904 | 0.92 | CCR2 (0.44) | CCR2HDAC8HDAC6HDAC1ALDH1A1 | |
| SCHEMBL6093252 | 0.92 | GRIN1 (0.45) | GRIN1GRIN2BCCR2HDAC8HDAC6 | |
| SCHEMBL6089650 | 0.91 | GRIN1 (0.44) | GRIN1GRIN2BCCR2HDAC8HDAC6 | |
| SCHEMBL6091368 | 0.89 | GRIN1 (0.43) | GRIN1GRIN2BHDAC8HDAC6HDAC1 | |
| SCHEMBL6092260 | 0.88 | SERPINE1 (0.43) | GRIN1GRIN2BPTGESP2RY14HPGD | |
| SCHEMBL6092477 | 0.88 | PTGER4 (0.43) | GRIN1GRIN2BPTGESP2RY14PTGER4 | |
| SCHEMBL6094279 | 0.87 | GRIN1 (0.42) | GRIN1GRIN2BCCR2ALDH1A1PTGES | |
| SCHEMBL6090994 | 0.87 | TP53 (0.46) | GRIN1GRIN2BPTGESKDM4EMAPT | |
| SCHEMBL6093213 | 0.86 | PTGES (0.55) | GRIN1GRIN2BPTGESCHRM3PTGER4 | |
| SCHEMBL6091457 | 0.86 | GRIN1 (0.41) | GRIN1GRIN2BHDAC8HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | GRIN1 1424/4885GRIN2B 2380/4885CCR2 377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.