Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4770473 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KDM4EALOX15HSD17B10HPGD | |
| SCHEMBL334850 | 0.81 | MAPT (0.74) | ALDH1A1KDM4EALOX15HSD17B10HPGD | |
| SCHEMBL15285555 | 0.81 | ALDH1A1 (0.68) | ALDH1A1KDM4EALOX15HSD17B10HPGD | |
| Ammonia Solution, Strong SCHEMBL7025659 | 0.79 | MAPT (0.72) | ALDH1A1KDM4EALOX15HSD17B10HPGD | |
| SCHEMBL9093746 | 0.78 | LMNA (0.71) | ALDH1A1KDM4EALOX15HSD17B10HPGD | |
| SCHEMBL610092 | 0.78 | ALDH1A1 (0.64) | ALDH1A1KDM4EALOX15HSD17B10HPGD | |
| Formaldehyde SCHEMBL4408279 | 0.78 | MAPT (0.70) | ALDH1A1KDM4EALOX15HSD17B10HPGD | |
| SCHEMBL10474728 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KDM4EALOX15HSD17B10HPGD | |
| SCHEMBL14982088 | 0.77 | MAPT (0.68) | ALDH1A1KDM4EALOX15HSD17B10HPGD | |
| SCHEMBL2742813 | 0.76 | NPC1 (0.66) | ALDH1A1KDM4EALOX15HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857446-B1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER IND (JP) | 2018-03-07 | — | — | EP | disclosed |
| US-9790359-B2 | Tread rubber composition and pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20150099823-A1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2015-04-09 | — | — | US | disclosed |
| EP-2857446-A1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | Sumitomo Rubber Industries, Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |
| US-8334339-B2 | Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer | SUMITOMO CHEMICAL CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| CN-102382258-A | Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer | SUMITOMO CHEMICAL CO | 2012-03-21 | — | — | CN | disclosed |
| US-20120041134-A1 | CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER COMPOSITION, AND PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |