SCHEMBL6091772

SCHEMBL6091772

C=C1N(C)c2cc(Cl)c(Cl)cc2C1(C)C

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5464264 0.86 MPI (0.56) MPITDP1
SCHEMBL6092178 0.78 MPI (0.50) MPITDP1
SCHEMBL3809912 0.78 POLB (0.43) MPITDP1
SCHEMBL4604551 0.74 MPI (0.47) MPITDP1
SCHEMBL4602685 0.73 TDP1 (0.45) MPITDP1
SCHEMBL4602213 0.70 TDP1 (0.43) MPITDP1
SCHEMBL5976671 0.70 MPI (0.34) MPITDP1
SCHEMBL4603122 0.70 MPI (0.50) MPITDP1
SCHEMBL2185507 0.70 TDP1 (0.43) MPITDP1PGR
SCHEMBL5975249 0.70 MPI (0.43) MPITDP1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2129187-A None JP disclosed
US-7132550-B2 Process for the preparation of cyanine dyes with polysulfonate anions EASTMAN KODAK COMPANY (US) 2006-11-07 US disclosed
EP-1535968-A2 Process for the preparation of cyanine dyes with polysulfonate anions Kodak Polychrome Graphics, LLC (US) 2005-06-01 EP disclosed
US-20050113546-A1 Process for the preparation of cyanine dyes with polysulfonate anions KODAK REALTY INC. 2005-05-26 US disclosed
US-5559231-A PHOTOCHROMIC, RECORDING MATERIAL, CLOTHING, GLASSES, WINDOWS TORAY INDUSTRIES, INC. (JP) 1996-09-24 US disclosed
EP-0358774-B1 NOVEL SPIROOXAZINE COMPOUNDS TORAY INDUSTRIES (JP) 1995-10-25 EP disclosed
US-5374723-A Photochromic dyes; resistance to repetition of coloration and discoloration TORAY INDUSTRIES, INC. (JP) 1994-12-20 US disclosed
JP-H02129187-A SPIROXAZINE COMPOUND TORAY IND INC 1990-05-17 JP disclosed
EP-0358774-A1 NOVEL SPIROOXAZINE COMPOUNDS TORAY INDUSTRIES, INC. (JP) 1990-03-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050113546-A1 Process for the preparation of cyanine dyes with polysulfonate anions MPST, ALG3, KIT MPI 1735/4885TDP1 4222/4885PGR 2321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.