SCHEMBL6092178

SCHEMBL6092178

C=C1N(C)c2cc(C)c(C)cc2C1(C)C

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5464264 0.87 MPI (0.56) MPITDP1KDM4EMEN1MAPT
SCHEMBL9333589 0.81 MPI (0.46) MPITDP1
SCHEMBL6091772 0.78 MPI (0.49) MPITDP1
SCHEMBL4602685 0.78 TDP1 (0.45) MPITDP1KDM4EMEN1MAPT
SCHEMBL4603835 0.77 KMT2A (0.53) MPITDP1KDM4EMEN1MAPT
SCHEMBL10670882 0.74 TSHR (0.38) MPITDP1MEN1HTTKMT2A
SCHEMBL4602669 0.73 MPI (0.38) MPITDP1KDM4EMEN1MAPT
SCHEMBL6660643 0.73 MAPT (0.42) TDP1KDM4EMEN1MAPTHTT
SCHEMBL4613468 0.73 MPI (0.44) MPITDP1KDM4EMAPTHTT
SCHEMBL9750449 0.73 MAPT (0.40) MPITDP1MEN1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3470471-B1 METHINE DYES LANXESS DEUTSCHLAND GMBH (DE) 2022-12-07 EP disclosed
CN-113943493-A Method for synthesizing spirooxazine photochromic dye by using microchannel reactor 广州盛色科技有限公司 2022-01-18 CN disclosed
US-7132550-B2 Process for the preparation of cyanine dyes with polysulfonate anions EASTMAN KODAK COMPANY (US) 2006-11-07 US disclosed
EP-1535968-A2 Process for the preparation of cyanine dyes with polysulfonate anions Kodak Polychrome Graphics, LLC (US) 2005-06-01 EP disclosed
US-20050113546-A1 Process for the preparation of cyanine dyes with polysulfonate anions KODAK REALTY INC. 2005-05-26 US disclosed
EP-0339661-B1 Photochromic substances RODENSTOCK OPTIK G (DE) 1994-04-20 EP disclosed
EP-0339661-A2 Photochromic substances Optische Werke G. Rodenstock (DE) 1989-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050113546-A1 Process for the preparation of cyanine dyes with polysulfonate anions MPST, ALG3, KIT MPI 1735/4885TDP1 4222/4885KDM4E 377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.