Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 10/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091406 | 0.85 | UTS2R (0.62) | UTS2RRAB9ANPC1CHRNB2CHRNB4 | |
| SCHEMBL6093310 | 0.84 | UTS2R (0.63) | UTS2RRAB9ANPC1MEN1KMT2A | |
| SCHEMBL6092762 | 0.84 | UTS2R (0.60) | UTS2RRAB9ANPC1MEN1KMT2A | |
| SCHEMBL6092713 | 0.81 | UTS2R (0.61) | UTS2RRAB9ANPC1MEN1KMT2A | |
| SCHEMBL6092652 | 0.80 | UTS2R (0.56) | UTS2RRAB9ANPC1MEN1KMT2A | |
| SCHEMBL6094333 | 0.80 | UTS2R (0.61) | UTS2RRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL6090694 | 0.79 | UTS2R (0.60) | UTS2RRAB9ANPC1MEN1KMT2A | |
| SCHEMBL5459450 | 0.77 | UTS2R (1.00) | UTS2R | |
| SCHEMBL6091970 | 0.76 | UTS2R (0.59) | UTS2RCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5458613 | 0.73 | UTS2R (0.63) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135694-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2006-12-21 | — | — | WO | claimed |
| WO-2006135694-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2006-12-21 | — | — | WO | disclosed |