Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.59 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090694 | 0.78 | UTS2R (0.60) | UTS2RCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6091146 | 0.78 | UTS2R (0.53) | UTS2RCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6091406 | 0.78 | UTS2R (0.62) | UTS2RCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6092440 | 0.76 | UTS2R (0.62) | UTS2RCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5455926 | 0.74 | UTS2R (1.00) | UTS2R | |
| SCHEMBL27558012 | 0.74 | CHRNB2 (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| SCHEMBL6092762 | 0.74 | UTS2R (0.60) | UTS2RALDH1A1LMNATP53 | |
| SCHEMBL28071194 | 0.73 | PLAU (0.64) | LMNA | |
| SCHEMBL14064867 | 0.73 | CHRM1 (0.54) | UTS2RCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6092713 | 0.73 | UTS2R (0.61) | UTS2RCHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135694-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2006-12-21 | — | — | WO | claimed |
| WO-2006135694-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2006-12-21 | — | — | WO | disclosed |