Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092762 | 0.87 | UTS2R (0.60) | UTS2RL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL6092440 | 0.84 | UTS2R (0.62) | UTS2RL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL6091406 | 0.82 | UTS2R (0.62) | UTS2RL3MBTL1ALDH1A1CRHBPCRHR2 | |
| SCHEMBL6092713 | 0.78 | UTS2R (0.61) | UTS2RL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL5449690 | 0.77 | UTS2R (1.00) | UTS2R | |
| SCHEMBL6094333 | 0.77 | UTS2R (0.61) | UTS2RL3MBTL1NPC1RAB9ACNR1 | |
| SCHEMBL6090694 | 0.76 | UTS2R (0.60) | UTS2RL3MBTL1HTTMEN1KMT2A | |
| SCHEMBL5465628 | 0.74 | UTS2R (0.64) | UTS2RL3MBTL1HTTMEN1KMT2A | |
| SCHEMBL6091970 | 0.73 | UTS2R (0.59) | UTS2RALDH1A1TP53CYP2C9CYP2C19 | |
| SCHEMBL6647977 | 0.71 | MTNR1B (0.82) | MTNR1BHTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135694-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2006-12-21 | — | — | WO | disclosed |