SCHEMBL609373

SCHEMBL609373

C=CCC1CCC(CC=C)NC1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16767293 0.80 DPP4 (0.36) DPP4L3MBTL1SMN1; SMN2
SCHEMBL2450241 0.77 GBA1 (0.32) L3MBTL1
SCHEMBL11817088 0.76 L3MBTL1 (0.36) L3MBTL1SMN1; SMN2
SCHEMBL10809053 0.74
SCHEMBL6839636 0.73
SCHEMBL432351 0.72
SCHEMBL815076 0.72 NOS1 (0.37)
SCHEMBL7283813 0.71 DPP4 (0.40) DPP4
SCHEMBL11653000 0.71 L3MBTL1 (0.41) L3MBTL1SMN1; SMN2
SCHEMBL11126675 0.71 L3MBTL1 (0.41) L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2421887-B1 METHOD FOR THE MANUFACTURE OF DEGARELIX POLYPEPTIDE LABORATORIES AS (DK) 2015-04-22 EP claimed
CN-102428097-B Method For The Manufacture Of Degarelix POLYPEPTIDE LABORATORIES A/S (DK) 2014-10-29 CN claimed
US-8828938-B2 Method for the manufacture of degarelix POLYPEPTIDE LABORATORIES A/S (DK) 2014-09-09 US claimed
CN-102428097-A Method for producing degarelix POLYPEPTIDE LABORATORIES AS (DK) 2012-04-25 CN claimed
EP-2421887-A1 METHOD FOR THE MANUFACTURE OF DEGARELIX Polypeptide Laboratories A/S (DK) 2012-02-29 EP claimed
US-20120041172-A1 METHOD FOR THE MANUFACTURE OF DEGARELIX POLYPEPTIDE LABORATORIES A/S (DK) 2012-02-16 US claimed
WO-2010121835-A1 METHOD FOR THE MANUFACTURE OF DEGARELIX POLYPEPTIDE LABORATORIES A/S (DK) 2010-10-28 WO claimed
US-4051140-A VANADIA CATALYST THE LUMMUS COMPANY (US) 1977-09-27 US claimed
US-20150158020-A1 SYNTHESIS OF ZEOLITES USING AN ORGANOAMMONIUM COMPOUND UOP LLC 2015-06-11 US disclosed
EP-2421887-B1 METHOD FOR THE MANUFACTURE OF DEGARELIX POLYPEPTIDE LABORATORIES AS (DK) 2015-04-22 EP disclosed
CN-102428097-B Method For The Manufacture Of Degarelix POLYPEPTIDE LABORATORIES A/S (DK) 2014-10-29 CN disclosed
US-8828938-B2 Method for the manufacture of degarelix POLYPEPTIDE LABORATORIES A/S (DK) 2014-09-09 US disclosed
EP-2421887-A1 METHOD FOR THE MANUFACTURE OF DEGARELIX Polypeptide Laboratories A/S (DK) 2012-02-29 EP disclosed
US-20120041172-A1 METHOD FOR THE MANUFACTURE OF DEGARELIX POLYPEPTIDE LABORATORIES A/S (DK) 2012-02-16 US disclosed
WO-2010121835-A1 METHOD FOR THE MANUFACTURE OF DEGARELIX POLYPEPTIDE LABORATORIES A/S (DK) 2010-10-28 WO disclosed
US-4057552-A AMMONIATION, OXIDIZED VANADIUM OXIDE ON SUPPORT AS CATALYST THE LUMMUS COMPANY (US) 1977-11-08 US disclosed
US-4051140-A VANADIA CATALYST THE LUMMUS COMPANY (US) 1977-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120041172-A1 METHOD FOR THE MANUFACTURE OF DEGARELIX DNPEP, PEPD, VIP DPP4 15/4885L3MBTL1 4433/4885SMN1; SMN2 3651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.