Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6093758 | 1.00 | SNCA (0.41) | SNCAPELI1ALDH1A1MAPTHPGD | |
| SCHEMBL6772802 | 0.88 | MMP13 (0.39) | MAPTHPGDMEN1KMT2AADAMTS4 | |
| SCHEMBL6772799 | 0.88 | MMP13 (0.39) | MAPTHPGDMEN1KMT2AADAMTS4 | |
| SCHEMBL6096687 | 0.81 | SNCA (0.42) | SNCAPELI1ALDH1A1MAPTHPGD | |
| SCHEMBL6096691 | 0.81 | SNCA (0.42) | SNCAPELI1ALDH1A1MAPTHPGD | |
| SCHEMBL6095126 | 0.80 | XDH (0.43) | SNCAPELI1ALDH1A1MAPTHPGD | |
| SCHEMBL6095120 | 0.80 | XDH (0.43) | SNCAPELI1ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL6097997 | 0.79 | XDH (0.42) | SNCAPELI1ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL6098003 | 0.79 | XDH (0.42) | SNCAPELI1ALDH1A1MAPTHPGD | |
| SCHEMBL6095986 | 0.77 | AURKA (0.45) | SNCAPELI1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7070626-B2 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-04 | — | — | US | disclosed |
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | KRT18, ALDH7A1, IK | SNCA 2855/4885PELI1 1293/4885ALDH1A1 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.