Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.72 |
| ▸ | TACR1 | P25103 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 5/20 | 0.52 |
| ▸ | CTSB | P07858 | 3/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6093920 | 1.00 | CTRB1 (0.72) | CTRB1TACR1CTSLCTSBCTSK | |
| SCHEMBL1570465 | 0.90 | CTRB1 (0.61) | CTRB1TACR1CTSLCTSBCTSK | |
| SCHEMBL1570467 | 0.90 | CTRB1 (0.61) | CTRB1TACR1CTSLCTSBCTSK | |
| SCHEMBL15664942 | 0.90 | CTRB1 (0.61) | CTRB1TACR1CTSLCTSBCTSK | |
| SCHEMBL1051352 | 0.88 | CTRB1 (0.76) | CTRB1TACR1CTSLCTSBCTSK | |
| SCHEMBL2482903 | 0.88 | CTRB1 (0.76) | CTRB1TACR1CTSLCTSBCTSK | |
| SCHEMBL2435512 | 0.88 | CTRB1 (0.76) | CTRB1TACR1CTSLCTSBCTSK | |
| SCHEMBL25302472 | 0.87 | CTRB1 (0.58) | CTRB1SYKATM | |
| SCHEMBL18956262 | 0.87 | CTRB1 (0.58) | CTRB1SYKATM | |
| SCHEMBL8842840 | 0.86 | CTRB1 (0.68) | CTRB1TACR1CTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005430-B2 | Fused purine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-02-28 | — | — | US | disclosed |
| US-20030176698-A1 | Fused purine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176698-A1 | Fused purine derivatives | PNP, NSUN2, CYP2W1 | CTRB1 1999/4885TACR1 2451/4885CTSL 2702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.