Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6096438 | 0.83 | MAPT (0.44) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL9996831 | 0.77 | MAPT (0.51) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL7961633 | 0.74 | TDP1 (0.56) | MAPTKMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL10781794 | 0.73 | TDP1 (0.49) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL10777343 | 0.73 | TDP1 (0.55) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL5889010 | 0.73 | ALDH1A1 (0.44) | MAPTKMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8119312 | 0.72 | CYP1A2 (0.57) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL6160971 | 0.71 | EPHX2 (0.55) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL2886975 | 0.70 | ALDH1A1 (0.56) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL10975098 | 0.70 | SMN1; SMN2 (0.49) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7070626-B2 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-04 | — | — | US | disclosed |