Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6095031 | 0.93 | MLLT1 (0.56) | HPGDHSD17B10ALDH1A1L3MBTL1MLLT1 | |
| SCHEMBL7704542 | 0.83 | HPGD (0.64) | HPGDHSD17B10ALDH1A1L3MBTL1TSHR | |
| SCHEMBL10957904 | 0.74 | HSD17B10 (0.54) | HPGDHSD17B10ALDH1A1L3MBTL1TSHR | |
| SCHEMBL2026474 | 0.72 | HPGD (1.00) | HPGDHSD17B10ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL13833222 | 0.71 | HPGD (0.97) | HPGDHSD17B10ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL383213 | 0.69 | DRD4 (0.77) | HPGDALDH1A1KDM4EDRD4HTT | |
| SCHEMBL6094092 | 0.68 | HPGD (0.54) | HPGDHSD17B10ALDH1A1L3MBTL1MLLT1 | |
| SCHEMBL23280193 | 0.68 | IDH1 (0.51) | PTGER4TSHRKDM4EMAPTHTT | |
| SCHEMBL521863 | 0.68 | KDM4E (0.79) | HPGDHSD17B10ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL6165371 | 0.68 | F2 (0.58) | HPGDALDH1A1TSHRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142365-A1 | Benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2006-06-29 | — | — | US | disclosed |
| US-7030150-B2 | Benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2006-04-18 | — | — | US | disclosed |
| US-20030119754-A1 | Benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142365-A1 | Benzimidazole compounds and antiviral uses thereof | MAVS, ZC3HAV1, TIMM13 | HPGD 4400/4885HSD17B10 4029/4885ALDH1A1 1618/4885 |
| US-20030119754-A1 | Benzimidazole compounds and antiviral uses thereof | MAVS, ZC3HAV1, TIMM13 | HPGD 4400/4885HSD17B10 4029/4885ALDH1A1 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.