Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL368032 | 0.88 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2D6FAAHNR1H2 | |
| SCHEMBL21651840 | 0.81 | MEN1 (0.53) | TBXA2RMEN1KMT2A | |
| SCHEMBL4065436 | 0.81 | CNR2 (0.46) | CYP1A2CYP3A4CYP2D6NR1H2HDAC6 | |
| SCHEMBL14838247 | 0.80 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2D6NR1H2HDAC6 | |
| SCHEMBL14300652 | 0.79 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2D6NR1H2HDAC6 | |
| SCHEMBL21651845 | 0.78 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2D6NR1H2HDAC6 | |
| SCHEMBL6951341 | 0.78 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2D6NR1H2HDAC6 | |
| SCHEMBL15294552 | 0.77 | NR1H2 (0.48) | CYP1A2CYP3A4CYP2D6NR1H2HDAC6 | |
| SCHEMBL4698252 | 0.76 | SMN1; SMN2 (0.47) | NR1H2MAPTKMT2AL3MBTL1CNR2 | |
| SCHEMBL6095249 | 0.76 | MAPT (0.47) | CYP1A2CYP3A4CYP2D6NR1H2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142365-A1 | Benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2006-06-29 | — | — | US | disclosed |
| US-7030150-B2 | Benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2006-04-18 | — | — | US | disclosed |
| US-20030119754-A1 | Benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2003-06-26 | — | — | US | disclosed |
| WO-2002092575-A1 | BENZIMIDAZOLE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS, INC. (US) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142365-A1 | Benzimidazole compounds and antiviral uses thereof | MAVS, ZC3HAV1, TIMM13 | CYP1A2 2306/4885CYP3A4 334/4885CYP2D6 1503/4885 |
| US-20030119754-A1 | Benzimidazole compounds and antiviral uses thereof | MAVS, ZC3HAV1, TIMM13 | CYP1A2 2306/4885CYP3A4 334/4885CYP2D6 1503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.