Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 11/20 | 0.67 |
| ▸ | CA1 | P00915 | 11/20 | 0.67 |
| ▸ | CA2 | P00918 | 11/20 | 0.67 |
| ▸ | CA9 | Q16790 | 11/20 | 0.67 |
| ▸ | CA7 | P43166 | 6/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | IKBKB | O14920 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 5/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143886 | 0.83 | HRH3 (0.54) | CA12CA1CA2CA9CA7 | |
| SCHEMBL7008138 | 0.83 | HRH3 (0.54) | IKBKBKEAP1NFE2L2HRH3LTA4H | |
| SCHEMBL5971888 | 0.83 | HRH3 (0.54) | KEAP1NFE2L2HRH3LTA4H | |
| SCHEMBL3143891 | 0.81 | HRH3 (0.53) | KEAP1NFE2L2HRH3LTA4H | |
| SCHEMBL9815651 | 0.81 | CA2 (0.66) | CA1CA2CA9CA7TSHR | |
| SCHEMBL5595956 | 0.80 | CA1 (1.00) | CA12CA1CA2CA9CA7 | |
| SCHEMBL615392 | 0.80 | CA2 (1.00) | CA12CA1CA2CA9CA7 | |
| SCHEMBL13588801 | 0.80 | HRH3 (0.51) | IKBKBKEAP1NFE2L2HRH3LTA4H | |
| SCHEMBL19891669 | 0.80 | CA12 (0.79) | CA12CA1CA2CA9CA7 | |
| Hydrochloric Acid SCHEMBL9256011 | 0.79 | HRH3 (0.50) | CA12CA2CA9KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10385016-B2 | Non explosive bis-sulfonyl azides | DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK (DE) | 2019-08-20 | — | — | US | disclosed |
| US-20180050988-A1 | NON EXPLOSIVE BIS-SULFONYL AZIDES | DYNAMIT NOBEL GMBH EXPLOSIVSTOFF- UND SYSTEMTECHNIK (DE) | 2018-02-22 | — | — | US | disclosed |
| US-7001917-B2 | Pyrazole compounds as anti-inflammatory and analgesic agents | WARNER LAMBERT COMPANY LLC (US) | 2006-02-21 | — | — | US | disclosed |
| EP-1495005-A1 | PYRAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | Pfizer Japan Inc. (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-20040019045-A1 | 2-(4-(4-(4-Fluorophenyl)-3,5-imethyl-1H-pyrazol-1-yl)phenyl) ethyl (4-methylphenyl)sulfonylcarbamate ammonium salt, e.g., as an antagonist for Prostoglandin E receptor; analgesics; antipyretics; antiinflammatory agents | HIRANO MISATO (JP) | 2004-01-29 | — | — | US | disclosed |
| WO-2003087061-A1 | PYRAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER JAPAN INC. (JP) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019045-A1 | 2-(4-(4-(4-Fluorophenyl)-3,5-imethyl-1H-pyrazol-1-yl)phenyl) ethyl (4-methylphenyl)sulfonylcarbamate ammonium salt, e.g., as an antagonist for Prostoglandin E receptor; analgesics; antipyretics; antiinflammatory agents | PTGER1, PTGS1, PTGIR | CA12 2871/4885CA1 1837/4885CA2 230/4885 |
| US-10385016-B2 | Non explosive bis-sulfonyl azides | ARSA, MSRB3, NES | CA12 3555/4885CA1 2823/4885CA2 1475/4885 |
| US-20180050988-A1 | NON EXPLOSIVE BIS-SULFONYL AZIDES | ARSA, MSRB3, NES | CA12 3519/4885CA1 2828/4885CA2 1444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.