Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | DDX3X | O00571 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14402886 | 0.88 | MAPT (0.65) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL1358811 | 0.86 | MAPT (0.63) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL30168176 | 0.86 | MAPT (0.63) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL24510782 | 0.86 | MAPT (0.68) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL11289487 | 0.84 | MAPT (0.51) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL11654725 | 0.83 | MAPT (0.59) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL15693306 | 0.83 | MAPT (0.84) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL1548172 | 0.83 | MAPT (1.00) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL3880896 | 0.82 | MAPT (0.82) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL9551205 | 0.82 | MAPT (0.67) | MAPTCYP1A2CYP2C9CYP2C19RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7070626-B2 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-04 | — | — | US | disclosed |
| US-6887281-B2 | N-heteroarylmethyl-p-phenylenediamine derivatives as well as oxidation dyeing agents containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-05-03 | — | — | US | disclosed |
| US-6849097-B2 | N-heteroarylmethyl-p-phnylendiamine derivatives and compounds containing oxidationcoloring agents | WELLA AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | disclosed |
| US-20050015898-A1 | N-heteroarylmethyl-p-phenylenediamine derivatives as well as oxidation dyeing agents containing these compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2005-01-27 | — | — | US | disclosed |
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-16 | — | — | US | disclosed |
| US-20030070240-A1 | N-heteroarylmethyl-p-phnylendiamine derivatives and compounds containing oxidationcoloring agents | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030070240-A1 | N-heteroarylmethyl-p-phnylendiamine derivatives and compounds containing oxidationcoloring agents | PNMT, PAH, CYP2E1 | MAPT 2997/4885CYP1A2 35/4885CYP2C9 12/4885 |
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | KRT18, ALDH7A1, IK | MAPT 666/4885CYP1A2 471/4885CYP2C9 697/4885 |
| US-20050015898-A1 | N-heteroarylmethyl-p-phenylenediamine derivatives as well as oxidation dyeing agents containing these compounds | TYR, PNMT, DDT | MAPT 3455/4885CYP1A2 149/4885CYP2C9 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.