Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | DDX3X | O00571 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321386 | 0.88 | DDX3X (0.57) | MAPTCYP1A2CYP2C9CYP2C19CASP1 | |
| SCHEMBL11781579 | 0.87 | MAPT (0.47) | MAPTCYP1A2CYP2C9CYP2C19CASP1 | |
| SCHEMBL36453118 | 0.86 | ALDH1A1 (0.55) | MAPTCYP1A2CYP2C9CYP2C19CASP1 | |
| SCHEMBL2306521 | 0.86 | ALDH1A1 (0.55) | MAPTCYP1A2CYP2C9CYP2C19CASP1 | |
| SCHEMBL6095592 | 0.84 | MAPT (0.70) | MAPTCYP1A2CYP2C9CYP2C19CASP1 | |
| SCHEMBL10780310 | 0.83 | HPGD (0.53) | MAPTCYP1A2CYP2C9CYP2C19CASP1 | |
| SCHEMBL6485998 | 0.83 | MAPT (0.77) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL4012730 | 0.82 | ALDH1A1 (0.49) | MAPTCYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL11689056 | 0.82 | GAA (0.50) | MAPTTSHRALDH1A1GAAHDAC1 | |
| SCHEMBL4015767 | 0.81 | DDX3X (0.67) | MAPTCYP1A2CYP2C9CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178455-A | FROM AROMATIC NITRO COMPOUND, ALCOHOL AND CARBON MONOXIDE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1979-12-11 | — | — | US | claimed |
| US-20240158355-A1 | BET SUBFAMILY INHIBITORS AND METHODS USING SAME | BAYLOR COLLEGE MEDICINE (US) | 2024-05-16 | — | — | US | disclosed |
| US-11944099-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | CORTEVA AGRISCIENCE LLC (US) | 2024-04-02 | — | — | US | disclosed |
| US-20230180761-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2023-06-15 | — | — | US | disclosed |
| US-11632957-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | CORTEVA AGRISCIENCE LLC (US) | 2023-04-25 | — | — | US | disclosed |
| WO-2022159454-A1 | BET SUBFAMILY INHIBITORS AND METHODS USING SAME | BAYLOR COLLEGE OF MEDICINE (US) | 2022-07-28 | — | — | WO | disclosed |
| EP-3971166-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO | Corteva Agriscience LLC (US) | 2022-03-23 | — | — | EP | disclosed |
| US-20210161144-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2021-06-03 | — | — | US | disclosed |
| US-10993440-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes related thereto | DOW AGROSCIENCES LLC (US) | 2021-05-04 | — | — | US | disclosed |
| US-20200196607-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2020-06-25 | — | — | US | disclosed |
| US-20170339961-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2017-11-30 | — | — | US | disclosed |
| US-9781935-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2017-10-10 | — | — | US | disclosed |
| WO-2016168059-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-10-20 | — | — | WO | disclosed |
| US-20160304522-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2016-10-20 | — | — | US | disclosed |
| EP-0000563-B1 | PROCESS FOR PREPARING AROMATIC URETHANES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1982-05-12 | — | — | EP | disclosed |
| EP-0000815-B1 | PROCESS FOR PREPARING N-ARYL OR N-ARALKYL SUBSTITUTED URETHANES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1982-01-27 | — | — | EP | disclosed |
| US-4227008-A | CATALYTIC REACTION OF A NITRO-, NITROSO-, OR CARBAMATE-CONTAINING AROMATIC PRIMARY AMINE, AN ALCOHOL, AND CARBON MONOXIDE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1980-10-07 | — | — | US | disclosed |
| US-4178455-A | FROM AROMATIC NITRO COMPOUND, ALCOHOL AND CARBON MONOXIDE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1979-12-11 | — | — | US | disclosed |
| EP-0000815-A1 | Process for preparing N-aryl or N-aralkyl substituted urethanes | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1979-02-21 | — | — | EP | disclosed |
| EP-0000563-A1 | Process for preparing aromatic urethanes | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1979-02-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158355-A1 | BET SUBFAMILY INHIBITORS AND METHODS USING SAME | BRDT, BRD3, BRD2 | MAPT 2774/4885CYP1A2 2451/4885CYP2C9 3970/4885 |
| US-11632957-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | MAPT 3431/4885CYP1A2 732/4885CYP2C9 379/4885 |
| US-10993440-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes related thereto | ACHE, DDT, MLYCD | MAPT 3414/4885CYP1A2 666/4885CYP2C9 250/4885 |
| US-11944099-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | MAPT 3431/4885CYP1A2 732/4885CYP2C9 379/4885 |
| US-20160304522-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | MAPT 3431/4885CYP1A2 732/4885CYP2C9 379/4885 |
| US-20210161144-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | ACHE, DDT, MLYCD | MAPT 3431/4885CYP1A2 732/4885CYP2C9 379/4885 |
| US-20230180761-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | ACHE, DDT, MLYCD | MAPT 3431/4885CYP1A2 732/4885CYP2C9 379/4885 |
| US-20200196607-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | ACHE, DDT, MLYCD | MAPT 3431/4885CYP1A2 732/4885CYP2C9 379/4885 |
| US-20170339961-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | MAPT 3431/4885CYP1A2 732/4885CYP2C9 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.