Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.38 |
| ▸ | MMP7 | P09237 | 6/20 | 0.38 |
| ▸ | MMP3 | P08254 | 5/20 | 0.38 |
| ▸ | MMP13 | P45452 | 4/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | OXTR | P30559 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 11/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4943932 | 0.84 | MMP1 (0.40) | MMP1MMP7MMP3MMP13MMP2 | |
| SCHEMBL4943934 | 0.84 | MMP1 (0.40) | MMP1MMP7MMP3MMP13MMP2 | |
| SCHEMBL4945463 | 0.84 | MMP1 (0.40) | MMP1MMP7MMP3MMP13MMP2 | |
| SCHEMBL4945461 | 0.84 | MMP1 (0.40) | MMP1MMP7MMP3MMP13MMP2 | |
| SCHEMBL4945246 | 0.80 | EPHX2 (0.38) | MMP1MMP7MMP3MMP13MMP2 | |
| SCHEMBL4943308 | 0.75 | OXTR (0.40) | MMP1MMP7MMP3MMP13OXTR | |
| SCHEMBL4943333 | 0.75 | OXTR (0.40) | MMP1MMP7MMP3MMP13OXTR | |
| SCHEMBL4943329 | 0.74 | MMP1 (0.41) | MMP1MMP7MMP3MMP13OXTR | |
| SCHEMBL4938441 | 0.74 | MMP1 (0.35) | MMP1MMP7MMP3MMP13MMP2 | |
| SCHEMBL4944190 | 0.73 | MMP1 (0.39) | MMP1MMP7MMP3MMP13CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018988-B2 | Pharmaceutically active pyrrolidine derivatives as Bax inhibitors | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-03-28 | — | — | US | disclosed |