Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6099003 | 0.85 | CCKBR (0.39) | RAB9ANPC1KMT2ACCKBRCFTR | |
| SCHEMBL6097770 | 0.79 | CCKBR (0.49) | RAB9ANPC1CCKBRHDAC6ALOX5AP | |
| SCHEMBL6097392 | 0.77 | CNR2 (0.36) | RAB9ANPC1KMT2ACCKBRCFTR | |
| SCHEMBL6097387 | 0.77 | CNR2 (0.36) | RAB9ANPC1KMT2ACCKBRCFTR | |
| SCHEMBL6099089 | 0.76 | RIPK1 (0.43) | KMT2ACCKBR | |
| SCHEMBL6097679 | 0.74 | CCKBR (0.40) | MEN1KMT2ACCKBRSMN1; SMN2KDM4E | |
| SCHEMBL6335210 | 0.73 | KMT2A (0.39) | RAB9AMEN1KMT2ACCKBRMAPT | |
| SCHEMBL6097590 | 0.73 | KMT2A (0.40) | RAB9AMEN1KMT2ACCKBRMAPT | |
| Lithium Ion SCHEMBL6335206 | 0.72 | KMT2A (0.39) | RAB9AMEN1KMT2ACCKBRMAPT | |
| SCHEMBL6094324 | 0.71 | CCKBR (0.57) | RAB9ANPC1MEN1KMT2ACCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034048-B2 | Gastrin and cholecystokinin receptor ligands (III) | JAMES BLACK FOUNDATION LIMITED (GB) | 2006-04-25 | — | — | US | disclosed |
| WO-2001085724-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS (III) | JAMES BLACK FOUNDATION LIMITED (GB) | 2001-11-15 | — | — | WO | disclosed |