Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NGFR | P08138 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873486 | 0.77 | CYP1A2 (0.48) | CYP1A2ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL11408828 | 0.76 | NTRK1 (0.52) | CYP1A2ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL13134034 | 0.76 | CYP1A2 (0.47) | CYP1A2ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL6520637 | 0.76 | CYP1A2 (0.47) | CYP1A2ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL31526985 | 0.76 | CYP1A2 (0.47) | CYP1A2ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL30297855 | 0.74 | CYP1A2 (0.46) | CYP1A2ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL28876218 | 0.74 | CYP1A2 (0.42) | CYP1A2ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL4079545 | 0.73 | CYP1A2 (0.44) | CYP1A2ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL4813089 | 0.73 | MAPT (0.45) | CYP1A2ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL6150350 | 0.72 | ALDH1A1 (0.45) | CYP1A2ALDH1A1KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7108846-B1 | Methods for preparing perfluorinated [18f]-radiolabelled nitroimidazole derivatives for cellular hypoxia detection | UNIVERSITE CATHOLIQUE DE LOUVAN (BE) | 2006-09-19 | — | — | US | disclosed |
| EP-1202945-B1 | METHODS FOR PREPARING PERFLUORINATED [18 F]-RADIOLABELLED NITROIMIDAZOLE DERIVATIVES FOR CELLULAR HYPOXIA DETECTION | UNIV CATHOLIQUE LOUVAIN (BE) | 2005-08-17 | — | — | EP | disclosed |
| EP-1202945-A1 | METHODS FOR PREPARING PERFLUORINATED [18 F]-RADIOLABELLED NITROIMIDAZOLE DERIVATIVES FOR CELLULAR HYPOXIA DETECTION | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001012575-A1 | METHODS FOR PREPARING PERFLUORINATED [18F]-RADIOLABELLED NITROIMIDAZOLE DERIVATIVES FOR CELLULAR HYPOXIA DETECTION | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2001-02-22 | — | — | WO | disclosed |