Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | NGFR | P08138 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HEXA | P06865 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11408828 | 0.89 | NTRK1 (0.52) | MAPTLMNACDC25AKDM4EALDH1A1 | |
| SCHEMBL4079545 | 0.81 | CYP1A2 (0.44) | MAPTKDM4EALDH1A1RAB9ANPSR1 | |
| SCHEMBL4950343 | 0.80 | ASAH1 (0.56) | CDC25AALDH1A1CYP1A2ASAH1CA12 | |
| SCHEMBL22649169 | 0.80 | CYP1A2 (0.43) | MAPTKDM4EALDH1A1RAB9ANPSR1 | |
| SCHEMBL8227448 | 0.80 | CYP1A2 (0.43) | MAPTLMNAKDM4EALDH1A1RAB9A | |
| SCHEMBL29612422 | 0.80 | GAA (0.53) | MAPTLMNAKDM4EALDH1A1RAB9A | |
| SCHEMBL30501189 | 0.79 | SIGMAR1 (0.44) | MAPTHTTLMNAKDM4EALDH1A1 | |
| SCHEMBL28876218 | 0.79 | CYP1A2 (0.42) | MAPTKDM4EALDH1A1RAB9ANPSR1 | |
| SCHEMBL27387263 | 0.79 | ASAH1 (0.59) | CDC25AALDH1A1CYP1A2ASAH1CA12 | |
| SCHEMBL8873486 | 0.79 | CYP1A2 (0.48) | MAPTLMNAKDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388112-B2 | Immunomodulation with novel pharmaceutical compositions | MEDIQUEST THERAPEUTICS, INC. (US) | 2008-06-17 | — | — | US | disclosed |
| US-20060167054-A1 | Immunomodulation with novel pharmaceutical compositions | MEDIQUEST THERAPEUTICS, INC. (US) | 2006-07-27 | — | — | US | disclosed |
| US-6919483-B2 | Immunomodulation with novel pharmaceutical compositions | MEDIQUEST THERAPEUTICS, INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20040235960-A1 | Immunomodulation with novel pharmaceutical compositions | MEDIQUIST THERAPRUTICS, INC. | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235960-A1 | Immunomodulation with novel pharmaceutical compositions | TNF, IL2, CD40 | MAPT 4581/4885HTT 2521/4885LMNA 3271/4885 |
| US-20060167054-A1 | Immunomodulation with novel pharmaceutical compositions | TNF, IL2, CD40 | MAPT 4809/4885HTT 2877/4885LMNA 3747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.