Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138997 | 0.88 | MAPT (0.41) | SMARCA2SMARCA4PBRM1CHRNA7MAPT | |
| SCHEMBL6096934 | 0.88 | CTSL (0.42) | GUSBCHRNA7MAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL6139196 | 0.87 | MAPT (0.43) | SMARCA2SMARCA4PBRM1CHRNA7MAPT | |
| SCHEMBL6096099 | 0.86 | SMARCA2 (0.36) | GUSBSMARCA2SMARCA4PBRM1CHRNA7 | |
| SCHEMBL6097293 | 0.83 | APP (0.38) | GUSBCHRNA7MAPTALDH1A1KDM4E | |
| SCHEMBL6096641 | 0.83 | NPC1 (0.51) | GUSBCHRNA7MAPTALDH1A1KDM4E | |
| SCHEMBL7065534 | 0.81 | BCHE (0.39) | CHRNA7 | |
| SCHEMBL6138772 | 0.81 | MAPT (0.39) | CHRNA7MAPTALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6139491 | 0.80 | MAPT (0.41) | CHRNA7MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL6098465 | 0.79 | KDM4E (0.43) | GUSBSMARCA2SMARCA4PBRM1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7070626-B2 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-04 | — | — | US | disclosed |
| EP-1286953-B1 | (P-AMINO-HYDROXYPHENYL)-ACRYLAMIDE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-02-18 | — | — | EP | disclosed |
| EP-1286953-A1 | (P-AMINO-HYDROXYPHENYL)-ACRYLAMIDE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2002079144-A1 | (P-AMINO-HYDROXYPHENYL)-ACRYLAMIDE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-10 | — | — | WO | disclosed |