Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | YWHAG | P61981 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6139491 | 0.99 | MAPT (0.41) | MAPTMEN1KMT2ATHRBUSP2 | |
| SCHEMBL6139384 | 0.94 | GAA (0.42) | MAPTMEN1KMT2ATHRBUSP2 | |
| Hydrochloric Acid SCHEMBL6139144 | 0.93 | GAA (0.41) | MAPTMEN1KMT2ATHRBUSP2 | |
| SCHEMBL6138997 | 0.92 | MAPT (0.41) | MAPTMEN1KMT2ATHRBUSP2 | |
| Hydrochloric Acid SCHEMBL6139196 | 0.91 | MAPT (0.43) | MAPTMEN1KMT2ATHRBUSP2 | |
| SCHEMBL6093384 | 0.82 | KDM4E (0.40) | MAPTMEN1KMT2ATHRBRECQL | |
| SCHEMBL6096099 | 0.82 | SMARCA2 (0.36) | MAPTMEN1KMT2ATHRBTDP1 | |
| SCHEMBL6139109 | 0.82 | MAPT (0.49) | MAPTMEN1KMT2ATHRBUSP2 | |
| Hydrochloric Acid SCHEMBL6092945 | 0.81 | KDM4E (0.39) | MAPTMEN1KMT2ATHRBRECQL | |
| Hydrochloric Acid SCHEMBL6139145 | 0.81 | MAPT (0.49) | MAPTMEN1KMT2ATHRBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263712-B1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2005-12-14 | — | — | EP | claimed |
| US-6699990-B2 | COLORFASTNESS; WATERPROOFING; OXIDATIVE COLOR HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-03-02 | — | — | US | claimed |
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-31 | — | — | US | claimed |
| EP-1263712-A1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2002-12-11 | — | — | EP | claimed |
| WO-2002074731-A1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-26 | — | — | WO | claimed |
| EP-1263712-B1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2005-12-14 | — | — | EP | disclosed |
| US-6699990-B2 | COLORFASTNESS; WATERPROOFING; OXIDATIVE COLOR HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-31 | — | — | US | disclosed |
| EP-1263712-A1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2002074731-A1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | DPYD, AOC1, GPX4 | MAPT 755/4885MEN1 4488/4885KMT2A 4214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.