Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.61 |
| ▸ | PDPK1 | O15530 | 8/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6097735 | 0.83 | PTGS1 (0.70) | PTGS2PTGS1PDPK1CYP2C9 | |
| SCHEMBL6097275 | 0.80 | PTGS1 (0.70) | PTGS2PTGS1PDPK1CYP2C9 | |
| SCHEMBL14504927 | 0.80 | PTGS2 (0.69) | PTGS2PTGS1PDPK1CYP2C9 | |
| SCHEMBL6097124 | 0.80 | PTGS2 (0.67) | PTGS2PTGS1PDPK1CYP2C9 | |
| SCHEMBL6098326 | 0.78 | PTGS1 (0.74) | PTGS2PTGS1PDPK1CYP2C9 | |
| Sulfamide SCHEMBL7139961 | 0.77 | PTGS1 (0.83) | PTGS2PTGS1PDPK1CYP2C9 | |
| SCHEMBL14504981 | 0.77 | PTGS2 (0.68) | PTGS2PTGS1PDPK1CYP2C9 | |
| SCHEMBL6451398 | 0.77 | PTGS1 (1.00) | PTGS2PTGS1PDPK1 | |
| SCHEMBL213784 | 0.77 | PTGS2 (1.00) | PTGS2PTGS1PDPK1CYP2C9 | |
| SCHEMBL8610309 | 0.77 | PTGS2 (1.00) | PTGS2PTGS1PDPK1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001917-B2 | Pyrazole compounds as anti-inflammatory and analgesic agents | WARNER LAMBERT COMPANY LLC (US) | 2006-02-21 | — | — | US | disclosed |