Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6908207 | 0.76 | — | — | |
| SCHEMBL2065172 | 0.72 | KDM4E (0.45) | KDM4EPIK3CDNQO2PER2CRY2 | |
| SCHEMBL29954446 | 0.69 | KDM4E (0.46) | KDM4EPIK3CDNQO2PER2CRY2 | |
| SCHEMBL5729061 | 0.69 | NPSR1 (0.47) | KDM4EPIK3CDPER2CRY2 | |
| SCHEMBL8903181 | 0.69 | KDM4E (0.43) | KDM4EPIK3CDNQO2PER2CRY2 | |
| SCHEMBL8593693 | 0.69 | — | — | |
| SCHEMBL3020556 | 0.68 | — | — | |
| SCHEMBL3295411 | 0.67 | — | — | |
| SCHEMBL509994 | 0.67 | — | — | |
| SCHEMBL261199 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030148-B2 | Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2006-04-18 | — | — | US | claimed |