Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.63 |
| ▸ | MAPK13 | O15264 | 12/20 | 0.63 |
| ▸ | MAPK12 | P53778 | 12/20 | 0.63 |
| ▸ | MAPK11 | Q15759 | 12/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6097639 | 0.92 | MAPK14 (0.58) | MAPK14MAPK13MAPK12MAPK11HDAC3 | |
| SCHEMBL6634484 | 0.88 | MAPK14 (0.57) | MAPK14MAPK13MAPK12MAPK11HDAC3 | |
| SCHEMBL6096393 | 0.88 | MAPK13 (0.59) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6634489 | 0.87 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11HDAC3 | |
| SCHEMBL6816785 | 0.86 | MAPK14 (0.68) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL6095812 | 0.85 | MAPK14 (0.59) | MAPK14MAPK13MAPK12MAPK11HDAC3 | |
| SCHEMBL6095615 | 0.85 | MAPK14 (0.72) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL6095607 | 0.85 | MAPK14 (0.72) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL2196830 | 0.84 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11HDAC3 | |
| SCHEMBL6095784 | 0.84 | MAPK14 (0.63) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034015-B2 | Interleukin 1 beta and tumour necrosis factor alpha inhibitors | LEO PHARMA A/S (DK) | 2006-04-25 | — | — | US | claimed |
| US-20030119902-A1 | Interleukin 1 beta and tumour necrosis factor alpha inhibitors | LEO PHARMA A/S (DK) | 2003-06-26 | — | — | US | claimed |
| US-7034015-B2 | Interleukin 1 beta and tumour necrosis factor alpha inhibitors | LEO PHARMA A/S (DK) | 2006-04-25 | — | — | US | disclosed |
| EP-1423356-A2 | NOVEL AMINOBENZOEPHENONES | Leo Pharma A/S (DK) | 2004-06-02 | — | — | EP | disclosed |
| US-20030119902-A1 | Interleukin 1 beta and tumour necrosis factor alpha inhibitors | LEO PHARMA A/S (DK) | 2003-06-26 | — | — | US | disclosed |
| WO-2003018535-A2 | NOVEL AMINOBENZOEPHENONES | LEO PHARMA A/S (DK) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119902-A1 | Interleukin 1 beta and tumour necrosis factor alpha inhibitors | IL1B, IL1A, TNF | MAPK14 1972/4885MAPK13 2918/4885MAPK12 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.